A patient was prescribed heparin sodium 18 units/kg/h; titrate according to the weight-based heparin protocol. The patient's weight is 123 pounds. Heparin 25,000 units/250 mL (100 units/mL) is available. Calculate the flow rate in mL/h (Round to the nearest tenths)
Explanation & Rationale
Given: Ordered dose of Heparin: 18 units/kg/hr Patient weight: 123 pounds Concentration of Heparin: 25,000 units/250 mL (100 units/mL) Step 1: Convert patient weight from pounds to kilograms: 1 pound (lb) = 0.453592 kilograms (kg) Patient weight in kg = 123 lbs x 0.453592 kg/lb = 55.7923 kg Step 2: Calculate the total dose of Heparin in units/hr: Total dose (units/hr) = Ordered dose (units/kg/hr) x Patient weight (kg) Total dose (units/hr) = 18 units/kg/hr x 55.7923 kg Total dose (units/hr) = 1004.2614 units/hr Step 3: Calculate the infusion rate in mL/hr: Infusion rate (mL/hr) = Total dose (units/hr) / Concentration (units/mL) Infusion rate (mL/hr) = 1004.2614 units/hr / 100 units/mL Infusion rate (mL/hr) = 10.042614 mL/hr Step 4: Round to the nearest tenths: Infusion rate (mL/hr) ≈ 10.0 mL/hr