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    NURS 5334-400 ADVANCED PHARMACOLOGY FOR NURSE PRACTIONERS Proctored Exam

    A patient who has a history of cardiac arrhythmias and heart failure has developed constipation. The health care provider instructs the patient that which of the following would be the MOST appropriate to use?

    Explanation & Rationale

    A. Sodium phosphate [Fleets Phospho-Soda]: Sodium phosphate is a hyperosmotic saline laxative that can cause significant fluid and electrolyte shifts, including hyperphosphatemia, hypocalcemia, and fluid overload. These effects can exacerbate heart failure and precipitate arrhythmias, making it unsafe for patients with cardiac conditions. B. Castor Oil: Castor oil is a stimulant laxative that increases intestinal motility but can cause cramping, nausea, and rapid fluid shifts. In patients with heart failure or cardiac arrhythmias, these fluid and electrolyte changes may worsen cardiac status or precipitate arrhythmias, so castor oil is generally avoided. C. Docusate sodium [Colace]: Docusate is a stool softener that facilitates water penetration into the stool without causing significant fluid or electrolyte disturbances. It is gentle and safe for patients with cardiac disease, making it the most appropriate option for constipation in someone with heart failure and arrhythmias. D. Magnesium citrate [Citrate of Magnesia]: Magnesium-containing saline laxatives can cause hypermagnesemia, especially in patients with impaired renal function or cardiac disease. Rapid shifts in electrolytes can increase the risk of arrhythmias and are potentially dangerous in heart failure, limiting its use in this population.

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