A pediatric patient weighing 22 kg is prescribed amoxicillin 50 mg/kg/day in divided doses every 8 hours. The medication is available as a suspension containing 125 mg/5 mL. How many mL of the suspension should the nurse administer for each dose?
Explanation & Rationale
Calculate the total daily dose in milligrams (mg). Total daily dose (mg) = Prescribed dose (mg/kg/day) × Weight (kg) = 50 mg/kg/day × 22 kg = 1100 mg/day. Determine the number of doses per day: Doses are given every 8 hours, so Number of doses per day = 24 hours / 8 hours = 3 doses/day. Calculate the dose per administration in milligrams (mg). Dose per administration (mg) = Total daily dose (mg) / Number of doses per day = 1100 mg / 3 doses = 366.666 mg. Available concentration of the amoxicillin suspension: = 125 mg / 5 mL. Calculate the volume in milliliters (mL) to administer for each dose. Volume per dose (mL) = Desired dose per administration (mg) / (Available concentration (mg) / Available volume (mL)) Volume per dose (mL) = 366.666 mg / (125 mg / 5 mL) = 366.666 mg × (5 mL / 125 mg) = (366.666 × 5) / 125 mL = 1833.33 / 125 mL = 14.666 mL. =14. 67 mL