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    ATI NUR 209 Maternal Newborn Proctored Exam

    A pregnant client at 28 weeks of gestation, who is receiving Rho(D) immune globulin for her Rh-negative status, asks the nurse if she will need another dose later.What is the most appropriate response from the nurse?

    Explanation & Rationale

    Choice A rationaleRho(D) immune globulin provides passive immunity against the Rh D antigen. The effects of a single dose administered at 28 weeks typically last for about 12 weeks, which generally covers the remainder of the pregnancy. However, it does not provide lifelong protection.Choice B rationaleWhile Rh-negative mothers receive Rho(D) immune globulin after events like bleeding or trauma that could lead to fetal-maternal hemorrhage, the standard protocol also includes a prophylactic dose at around 28 weeks gestation regardless of such events.Choice C rationaleIf the baby is Rh-positive, fetal red blood cells may enter the mother's circulation during delivery. To prevent the mother from developing Rh antibodies that could affect future Rh-positive pregnancies, another dose of Rho(D) immune globulin is necessary within 72 hours postpartum.Choice D rationaleRho(D) immune globulin given at 28 weeks primarily protects the current pregnancy. While it helps prevent sensitization that could affect future pregnancies, the 72-hour postpartum dose is specifically timed to address potential exposure to fetal Rh-positive blood during delivery of an Rh-positive infant.

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