A prescription indicates that a patient should receive Phenergan® 12.5 mg pr for nausea and vomiting. By what route should this medication be administered?

A. topically: Topical administration involves applying medication to the skin surface, typically for local effects. "pr" (per rectum) does not refer to topical use. B. transdermally: Transdermal delivery uses patches that release medication through the skin into the bloodstream over time. Phenergan® is not ordered in a transdermal form here, and "pr" does not support this route. C. through the rectum: The abbreviation "pr" stands for per rectum, which means the medication should be administered into the rectum. This is the correct route for Phenergan® suppositories prescribed for nausea and vomiting. D. through the vagina: Vaginal administration is typically indicated with terms like "pv" (per vagina). "pr" specifically refers to rectal administration.