A primary health-care provider prescribes a medication that must be administered transdermal. Which information about the route of administration does the nurse understand is related to a drug prescribed to be administered transdermal?

Choice A reason: Inhalation targets lungs; transdermal means skin absorption, not respiratory, and this route doesn’t match the prescribed method’s pharmacokinetic profile. Choice B reason: Transdermal drugs absorb through skin layers; this delivers medication systemically via dermal capillaries, bypassing first-pass metabolism, as intended by the order. Choice C reason: Rectal administration uses suppositories; transdermal is skin-based, not mucosal, and this route doesn’t align with the prescribed absorption method. Choice D reason: Sublingual dissolves under the tongue; transdermal is cutaneous, not oral, and this differs entirely from the skin-based delivery system specified.