A school nurse is talking with a 13-year-old female at her annual health-screening visit. Which of the following comments made by the adolescent should be the nurse's priority to address?

Choice A reason: Delayed menarche at age 13 is within normal developmental variation. Although it may cause concern for the adolescent, it is not an immediate priority unless accompanied by other signs of delayed puberty. Choice B reason: Expressing social isolation and rejection is a priority because it may indicate depression or risk for self-harm. Adolescents who feel excluded and disliked are more vulnerable to mental health crises. Choice C reason: Perceiving parents as overprotective is common in adolescence as teenagers seek independence. This is not typically a clinical concern. Choice D reason: Concerns about acne and appearance are common during adolescence and usually reflect normal developmental self-consciousness rather than a safety issue.