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    Paediatrics & maternity proctored exam (examplify)

    A toddler is being treated for acetaminophen toxicity after an accidental overdose. The nurse should prepare to administer which medication?

    Explanation & Rationale

    Choice A rationale Succimer is a chelating agent used to treat heavy metal poisoning, such as lead or arsenic toxicity. It works by binding to these metals and facilitating their excretion from the body. It is not indicated for the treatment of acetaminophen toxicity, which requires a different mechanism of action to counteract the toxic metabolite. Choice B rationale Atropine is an anticholinergic medication used to treat bradycardia or to counteract the effects of cholinergic drugs. It works by blocking the action of acetylcholine at muscarinic receptors. Its mechanism of action is unrelated to acetaminophen toxicity and it would not be an appropriate treatment. Choice C rationale Syrup of ipecac is an emetic used to induce vomiting. The use of emetics is no longer recommended for the treatment of most poisonings due to the risk of aspiration and lack of evidence for improved outcomes. Its use is contraindicated in cases of acetaminophen toxicity. Choice D rationale Acetylcysteine is the antidote for acetaminophen toxicity. It works by replenishing glutathione stores in the liver. Glutathione is essential for detoxifying the toxic metabolite of acetaminophen, N-acetyl-p-benzoquinone imine (NAPQI). A normal serum acetaminophen level is less than 10 mcg/mL.

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