Albumin 25% IV is prescribed for a child with nephrotic syndrome. Which assessment finding indicates to the nurse that the medication is having the desired effect?

Rationale: A. Reduction of fever: Albumin administration does not treat fever. Fever may indicate infection, which is a concern in children with nephrotic syndrome, but it is not an expected effect of albumin therapy. B. Reduction of edema: Albumin 25% IV increases plasma oncotic pressure, drawing fluid from the interstitial spaces back into the intravascular compartment. A decrease in edema demonstrates that the medication is effectively restoring fluid balance. C. Improved caloric intake: While improved nutrition supports overall health, albumin therapy does not directly influence the child’s appetite or caloric intake. Nutritional status should be monitored separately. D. Weight gain: Weight gain in nephrotic syndrome may indicate fluid retention rather than therapeutic effect. The desired outcome of albumin therapy is fluid mobilization and reduction of edema, not increased weight.