An adult client receives a prescription for diphenhydramine 15 mL by mouth every 12 hours PRN for pruritus. The bottle is labeled, diphenhydramine 12.5 mg/5 mL. What is the total daily dose in mg that the client receives? (Enter numerical value only.)

- Formula: Dose (mg) = Volume (mL) x Concentration (mg/mL) - Solution: - Dose (mg) = 15 mL x (12.5 mg / 5 mL) - Dose (mg) = 15 mL x 2.5 mg/mL - Dose (mg) = 37.5 mg - Answer: The client receives 37.5 mg of diphenhydramine every 12 hours PRN for pruritus. The total daily dose in mg is 37.5 x 2 = 75 mg.