An client who weighs 160 pounds receives a prescription for gentamicin 5 mg/kg/day IV in divided doses every 8 hours. How many mg should the nurse administer with each dose? (Enter numerical value only. If rounding is required, round to the nearest whole number.)

Convert the client's weight from pounds to kilograms: Weight (kg) = Weight (pounds) / 2.2 pounds/kg = 160 pounds / 2.2 pounds/kg ≈ 72.73 kg Calculate the total daily dose in milligrams: Total daily dose (mg) = Prescribed dose (mg/kg/day) x Client's weight (kg) = 5 mg/kg/day x 72.73 kg ≈ 363.65 mg/day Determine the number of doses per day: Number of doses per day = 24 hours / Frequency of doses (hours) = 24 hours / 8 hours/dose = 3 doses/day Calculate the dose to administer with each dose: Dose per administration (mg) = Total daily dose (mg) / Number of doses per day = 363.65 mg / 3 doses ≈ 121.22 mg Round to the nearest whole number: = 121 mg