Dopamine 5 mcg/kg/minute IV is prescribed for a client who weighs 132 pounds. The pharmacy dispenses a "Dopamine 1600 mg in 500 mL 0.9% normal saline IV solution." The nurse should program the infusion pump to deliver how many mL/hour? (Enter numeric value only. If rounding is required, round to the nearest tenth.)
Explanation & Rationale
Rationale: Convert the client's weight from pounds (lb) to kilograms (kg). Weight in kg = 132 lb / 2.2 lb/kg = 60 kg. Calculate the desired dose per minute in micrograms (mcg). Desired dose per minute (mcg/min) = Desired dose (mcg/kg/min) × Weight (kg) = 5 mcg/kg/min × 60 kg = 300 mcg/min. Convert the desired dose from micrograms per minute (mcg/min) to milligrams per hour (mg/hr). 1 mg = 1000 mcg 1 hr = 60 min Desired dose in mg/hr = (300 mcg/min / 1000 mcg/mg) × 60 min/hr = 0.3 mg/min × 60 min/hr = 18 mg/hr. Determine the concentration of the available Dopamine solution in milligrams per milliliter (mg/mL). Available concentration = Total medication (mg) / Total volume (mL) = 1600 mg / 500 mL = 3.2 mg/mL. Calculate the IV pump rate in milliliters per hour (mL/hr). IV pump rate (mL/hr) = Desired dose (mg/hr) / Available concentration (mg/mL) = 18 mg/hr / 3.2 mg/mL = 5.625 mL/hr. Round the answer to the nearest tenth. = 5.6