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    Hesi bsn 315 rn pharmacology 35504 proctored exam

    Exhibits Review H and P, nurse's notes, and prescriptions. Drag from Word Choices to complete the sentence. The thiazide diuretic works to decrease the client's blood pressure by dropdownand the angiotensin converting enyzme (ACE) inhibitor works to decrease the client's blood pressure by dropdownanddropdown.

    Explanation & Rationale

    • Decreasing serum sodium levels: Thiazide diuretics reduce blood pressure primarily by promoting the excretion of sodium and water through the kidneys. This decreases blood volume, leading to lower blood pressure by reducing preload and overall circulatory volume. • Reducing systemic vascular resistance: ACE inhibitors like lisinopril lower blood pressure by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This results in vasodilation and reduced systemic vascular resistance, decreasing the workload on the heart. • Increasing heart rate: Neither thiazide diuretics nor ACE inhibitors primarily increase heart rate. In fact, reflex tachycardia may occur but is not their main mechanism of blood pressure reduction. • Reducing stroke volume: ACE inhibitors reduce blood pressure by decreasing both systemic vascular resistance and stroke volume through afterload reduction and mild diuretic effect, which reduces cardiac workload. • Suppressing the appetite: Neither drug class acts by suppressing appetite. Weight management is important for hypertension control but is unrelated to the direct pharmacologic effects of these medications.

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