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    Pharmacology proctored exam (exemplify)

    For which condition should naloxone be administered?

    Explanation & Rationale

    A. Respiratory distress: Naloxone is an opioid antagonist used to reverse life-threatening respiratory depression caused by opioid overdose. Opioids can suppress the medullary respiratory center, leading to hypoventilation and hypoxia, and naloxone competitively displaces the opioid from receptors to restore normal respiration. B. Blurry vision: Blurred vision is not an indication for naloxone administration. It may result from ocular or neurological conditions but does not involve opioid toxicity requiring reversal. C. Gastrointestinal bleeding: Gastrointestinal bleeding is unrelated to opioid overdose. Naloxone does not affect bleeding risk or treat hemorrhagic events, so it would not be indicated. D. Confusion: While confusion may accompany opioid toxicity, it is nonspecific and not the primary indication. Naloxone is administered primarily for significant respiratory compromise rather than altered mental status alone.

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