Nur 114 dosage calculation proctored exam
Calculation
Heparin has been infusing at 15 units/kg/hr using 25,000 units heparin in 250 mL D5W. The patient weighs 75 kg. Adjust the infusion rate based on the new aPTT result of 43 seconds. Include the rate in mL/hr after adjustment. APTT less than 35 sec: Rebolus with 80 units/kg and increase rate by 4 units/kg/hr. APTT 35-45 sec: Rebolus with 40 units/kg and increase rate by 2 units/kg/hr. APTT 46-70 sec: No change. APTT 71-90 sec: Decrease rate by 2 units/kg/hr. APTT greater than 90 sec: Stop heparin infusion for 1 hour and decrease rate by 3 units/kg/hr. Do not provide the unit of measure. Only provide the number. Round to one decimal place (tenths).
mL/hr
Explanation & Rationale
Step 1: Patient weight = 75 kg Step 2: Current order = 15 units/kg/hr → 15 × 75 = 1125 units/hr Step 3: Adjustment based on aPTT = 43 sec (range 35–45 sec) → Rebolus with 40 units/kg and increase rate by 2 units/kg/hr Step 4: New rate in units/kg/hr 15 + 2 = 17 units/kg/hr Step 5: Convert to total units/hr 17 × 75 = 1275 units/hr Step 6: Concentration of solution 25,000 units ÷ 250 mL = 100 units/mL Step 7: Convert to mL/hr 1275 ÷ 100 = 12.75 ≈ 12.8 Final Answer: 12.8
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