If injection sites are not rotated regularly, the patient with diabetes mellitus may suffer from which of the following?

A. Lipodystrophy: Lipodystrophy refers to a localized loss of fat tissue or a change in the distribution of fat tissue due to repeated injections at the same site. In patients with diabetes mellitus, injecting insulin into the same site repeatedly can lead to lipodystrophy, affecting insulin absorption and glycaemic control. B. Petechiae: Petechiae are small, red or purple spots that appear on the skin due to bleeding under the skin. They are not typically associated with injection site issues but rather with conditions such as thrombocytopenia or blood clotting disorders. C. Hematoma: Hematoma is a localized collection of blood outside the blood vessels, often resulting from injury or trauma. It can occur at injection sites if a blood vessel is inadvertently punctured during the injection process. D. Pustules: Pustules are small, pus-filled lesions on the skin, usually associated with infections such as acne or folliculitis. They are not typically related to injection site issues in patients with diabetes mellitus.