In a child with cystic fibrosis what enzyme is necessary for digestion of fat and absorption of nutrients and is taken prior to meals?

A. Pancrelipase is correct. Children with cystic fibrosis (CF) often have exocrine pancreatic insufficiency, which impairs the digestion of fats, proteins, and carbohydrates. Pancrelipase contains lipase, protease, and amylase, which help digest these macronutrients and improve nutrient absorption. It is typically administered with every meal and snack to maximize digestion and caloric intake. B. Trypsin is incorrect because, while it is a digestive enzyme produced by the pancreas, it is not administered as a standalone medication for CF. Pancrelipase provides trypsin along with other enzymes in the proper combination for effective digestion. C. Acetaminophen is incorrect. This is an analgesic and antipyretic, unrelated to digestion or nutrient absorption. D. Elexacaftor is incorrect. Elexacaftor is a CFTR modulator used in combination with other drugs (like tezacaftor and ivacaftor) to improve cellular chloride transport in CF, but it does not replace digestive enzymes or aid directly in fat absorption.