Insulin glargine is prescribed for a hospitalized patient who has diabetes. When will the nurse expect to administer this drug?

Choice A reason: Insulin glargine is a long-acting insulin given once daily, not twice daily. Morning and 4:00 PM dosing is typical for intermediate-acting insulins, so this incorrect for glargine’s schedule. Choice B reason: Rapid-acting insulins are given before meals, not glargine, which provides basal coverage. Glargine is dosed once daily, so this is incorrect. Choice C reason: Post-meal or after meals and bedtime dosing does not suit glargine’s 24-hour action. It’s given once daily, typically at bedtime, so this is incorrect for the administration timing. Choice D reason: Insulin glargine is administered once daily, often at bedtime, to provide steady basal insulin coverage for 24 hours. This aligns with its pharmacokinetics, making it the correct choice.