It is important that a patient taking the mood stabilizer valproic acid (Depakote) has which of the following lab tests monitored every 6 months due to potential side effects?

Choice A reason: Glucose and HbA1c are monitored for diabetes, not for valproic acid. While weight gain can occur, these labs are not specific to Depakote’s primary risks. Choice B reason: GFR and creatinine assess renal function, which is more relevant for lithium monitoring. Valproic acid is hepatotoxic, not nephrotoxic. Choice C reason: CBC and liver function tests are essential for monitoring Depakote. The drug can cause hepatotoxicity and thrombocytopenia. Regular monitoring helps detect early signs of liver damage and blood dyscrasias. Choice D reason: TSH and T4 are relevant for lithium, which can affect thyroid function. Valproic acid does not typically impact thyroid hormones.