KB is a 60 kg newly diagnosed Type 1 insulin naive diabetic female that you plan to initiate a basal-bolus insulin regimen. You decide to initiate a total daily insulin dose of 0.5 units/kg/day. What would her bolus insulin dose be for lunch (assume she has 3 meals per day)?

Rationale: A. The total daily dose (TDD) is 30 units (60 kg x 0.5 units/kg). In a standard basal-bolus regimen, 50% of the TDD is basal (15 units) and 50% is bolus (15 units) divided among meals. Since she consumes 3 meals, the 15 units of bolus insulin is divided by 3, resulting in 5 units per meal. B. A bolus of 10 units per meal would result in a total mealtime insulin dose of 30 units per day. This would represent 100% of the calculated total daily dose for this patient, leaving no room for the necessary basal insulin component. Such a high bolus dose in an insulin-naive patient would significantly increase the risk of severe postprandial hypoglycemia. C. A dose of 30 units represents the entire total daily insulin requirement for this 60 kg patient based on the 0.5 units/kg calculation. Administering the entire TDD as a single bolus dose for lunch would be clinically dangerous and pharmacologically incorrect. This volume of insulin would exceed her physiological needs and fail to provide the background basal coverage required for Type 1 diabetes. D. A 15-unit dose represents the total amount of bolus insulin required for the entire day, not for a single meal. In a balanced 50/50 regimen, this 15-unit total must be distributed across the carbohydrate-containing meals to manage postprandial glucose excursions. Providing all 15 units at lunch would leave the patient without coverage for breakfast and dinner, leading to poor glycemic control.