Match each characteristic with the correct condition:
Explanation & Rationale
Rheumatoid Arthritis (RA) is a systemic autoimmune condition characterized by chronic synovial inflammation and symmetrical joint destruction. In contrast, Osteoarthritis (OA) is a localized degenerative process resulting from mechanical wear and tear of the articular cartilage. These conditions are differentiated clinically by the duration of morning stiffness and the specific joints affected. Osteoarthritis (OA): This wear-and-tear disease typically affects weight-bearing joints like the hips and knees (D). Morning stiffness is brief, usually resolving in less than 30 minutes once the joint is moved (B). These findings reflect the non-inflammatory, mechanical nature of the cartilaginous breakdown in OA. Rheumatoid Arthritis (RA): As an autoimmune disease (C), the body's immune system attacks the joint linings, causing significant systemic symptoms. This inflammation leads to prolonged morning stiffness that lasts more than 1 hour (A). The stiffness is often widespread and requires significant activity to alleviate.