Match each medication with it's indication, teaching or side effect. Use each option once. Prompts Possible Answers Disulfuram dropdown Buprenorphine-naloxone dropdown Chlordiazepoxide dropdown Methadone dropdown

Rationale for correct choices • Disulfiram: Disulfiram inhibits the enzyme acetaldehyde dehydrogenase, causing accumulation of acetaldehyde when alcohol is ingested. This leads to flushing, nausea, vomiting, hypotension, palpitations, and headaches. Teaching focuses on avoiding alcohol in beverages, foods, cough syrups, and topical products to prevent these potentially severe reactions. • Buprenorphine-naloxone:Buprenorphine-naloxone is a partial opioid agonist combined with an opioid antagonist. It reduces withdrawal symptoms and cravings while preventing abuse due to the naloxone component. It stabilizes the client for outpatient therapy, lowers overdose risk, and facilitates gradual recovery by modulating opioid receptor activity without producing the same euphoric effect as full agonists. • Chlordiazepoxide: Chlordiazepoxide is a benzodiazepine that enhances GABA-mediated CNS inhibition. Common side effects include sedation, impaired motor coordination, dizziness, and mild cognitive slowing. These effects increase fall risk, especially in older adults, and require nursing precautions such as monitoring ambulation and advising against driving or operating machinery during therapy. • Methadone: Methadone is a long-acting opioid agonist that binds to mu-opioid receptors, alleviating withdrawal symptoms and cravings in opioid use disorder. It is also used for chronic pain management due to its analgesic properties. Methadone reduces illicit opioid use, prevents acute withdrawal, and allows for controlled dosing in outpatient maintenance programs while requiring monitoring for QT prolongation and respiratory depression.