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    Pharmacology Exam 2 (Dallas University) Proctored Exam

    Match each medication with it's side effect. Medication Side Effect Valproate dropdown Vigabatrin dropdown Phenytoin dropdown Carbamazepine dropdown

    Explanation & Rationale

    Rationale: • Valproate – Pancreatitis: Valproate can cause inflammation of the pancreas, leading to symptoms such as abdominal pain, nausea, vomiting, and elevated pancreatic enzymes. This serious adverse effect requires prompt recognition, as continued use can result in severe complications, including pancreatic necrosis. • Vigabatrin – Vision loss: Vigabatrin is associated with permanent peripheral visual field constriction due to retinal toxicity. Regular ophthalmologic monitoring is recommended for early detection of vision changes to prevent irreversible damage. • Phenytoin – Gingival hyperplasia: Chronic phenytoin use can lead to overgrowth of gum tissue, particularly in the anterior teeth region. This occurs due to fibroblast stimulation in the gingiva and can be mitigated with proper oral hygiene and dental care. • Carbamazepine – Bone marrow depression: Carbamazepine can suppress bone marrow, leading to leukopenia, anemia, or thrombocytopenia. Monitoring complete blood counts is necessary to detect hematologic toxicity early and prevent complications such as infections or bleeding.

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