Maya's parents state she becomes irritable and aggressive in response to sensory challenges and changes in routine. They are interested in learning about all of the available options to support her safety and well-being. The nurse anticipates providing education on which medications that are FDA-approved for irritability in Autism Spectrum Disorders (ASD)?

A. Haloperidol (Haldol) and diphenhydramine (Benadryl): Haloperidol is an antipsychotic sometimes used off-label for severe behavioral disturbances, but it is not FDA-approved specifically for irritability in ASD. Diphenhydramine is an antihistamine used for allergies or sedation, not for managing irritability related to autism. B. Methylphenidate (Ritalin) and atomoxetine (Strattera): These medications are primarily indicated for attention-deficit/hyperactivity disorder (ADHD). They may improve attention and hyperactivity symptoms but are not FDA-approved for irritability or aggression in ASD. C. Sertraline (Zoloft) and fluoxetine (Prozac): These selective serotonin reuptake inhibitors are used to treat anxiety and depression. While they may be used off-label in ASD for repetitive behaviors or anxiety, they are not approved specifically for irritability or aggression in autism. D. Risperidone (Risperdal) and aripiprazole (Abilify): Both are atypical antipsychotics approved by the FDA to treat irritability, aggression, and self-injurious behavior in children and adolescents with Autism Spectrum Disorder. They target behavioral dysregulation and help improve safety and overall functioning.