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    Pharmacology proctored exam (exemplify)
    Select All That Apply

    Medical History: Thyroidectomy 6 months ago, seasonal allergies Current Medications: Levothyroxine Current Visit: Client presents to clinic with diarrhea, excessive sweating, and muscle pain; reports occasional palpitations started about 1 week ago. Client Profile Nursing Notes Name: Christopher Brown Age: 36 years Provider. M. Jensen, M.D. Allergies: Shellfish Code Status: Full code Weight: 88 ka (194 lb) Review the electronic health record. Which clinical finding(s) indicate levothyroxine toxicity? Select all that apply.

    Explanation & Rationale

    A. Occasional palpitations: Palpitations are a common sign of levothyroxine toxicity because excessive thyroid hormone increases cardiac output and sympathetic activity, leading to an elevated heart rate and irregular heart rhythms, which can be dangerous if untreated. B. Seasonal allergies: Seasonal allergies are unrelated to levothyroxine therapy. They are a chronic, immune-mediated response to environmental allergens and do not indicate thyroid hormone toxicity. C. Muscle pain: Muscle aches or weakness can occur with levothyroxine overdose due to hypermetabolism, increased protein catabolism, and overstimulation of muscle activity, making this a relevant symptom of toxicity. D. Excessive sweating: Hyperthyroid-like symptoms, including diaphoresis, occur with levothyroxine toxicity as a result of increased basal metabolic rate and overstimulation of sympathetic nervous system activity. E. Diarrhea: Increased gastrointestinal motility is a hallmark of levothyroxine overdose. Clients may experience frequent loose stools or diarrhea due to the hypermetabolic state induced by excess thyroid hormone.

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