Monroe-Kellie hypothesis and ICP: (Select all that apply, some, one, none)
Explanation & Rationale
A. Normal ICP 0-15 mmHg: Normal intracranial pressure in adults ranges from 0 to 15 mm Hg. Values above this range indicate increased ICP and may compromise cerebral perfusion. B. None: This option does not provide relevant information regarding the Monroe-Kellie hypothesis or ICP. C. If the volume and pressure of one component increases, the volume and the pressure of the other 2 components must decrease if pressure is to remain normal; compensation is a function of compliance: The Monroe-Kellie hypothesis states that the cranial vault is a fixed space containing brain tissue, blood, and cerebrospinal fluid (CSF). An increase in one component requires a compensatory decrease in others to maintain normal ICP. D. None: This option does not provide relevant information regarding ICP or the Monroe-Kellie hypothesis. E. Ptissue + Pblood + PCSF = ICP (80%/10%/10%): The total ICP is the sum of the pressures contributed by brain tissue (~80%), blood (~10%), and CSF (~10%). This relationship reflects the distribution of intracranial components under normal conditions.