NSAIDs are called nonsteroidal inflammatory drugs because they:
Explanation & Rationale
A. Treat inflammation without a risk of bleeding: NSAIDs are used to treat inflammation, pain, and fever, but their use does carry risks, such as gastrointestinal bleeding and kidney injury, especially with prolonged use. B. Treat inflammation without steroids: NSAIDs are called nonsteroidal because they reduce inflammation without being corticosteroids. They work by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), unlike steroids, which act through broader immunosuppressive mechanisms. C. They are never used to treat fever: NSAIDs are commonly used to treat fever as well as inflammation and pain. Drugs like ibuprofen and naproxen are effective antipyretics. D. Contain aspirin: While aspirin is classified as an NSAID, not all NSAIDs contain aspirin. There are many NSAIDs like ibuprofen and naproxen that do not contain aspirin but share similar anti-inflammatory and analgesic properties.