Ordered: Amoxicillin 250 mg tid for 7 days On hand: See label Note: Partial bottles are not dispensed. How much amoxicillin should be dispensed?
Explanation & Rationale
Rationale: Calculate the total milligrams of amoxicillin needed for the entire prescription. Given: Ordered dose is 250 mg. Frequency is three times a day (tid). Duration is 7 days. Total milligrams needed = 250 mg/dose × 3 doses/day × 7 days = 5250 mg. Determine the concentration of the medication from the label. The label states the concentration is 250 mg per 5 mL. Concentration = 250 mg / 5 mL = 50 mg/mL. Calculate the total volume in milliliters (mL) required for the prescription. Total volume needed = Total milligrams needed / Concentration = 5250 mg / 50 mg/mL = 105 mL. Determine the amount to dispense based on the bottle size and dispensing instructions. The label indicates that each reconstituted bottle contains 100 mL. The total volume needed is 105 mL, which is more than what one 100 mL bottle contains. The note states, "Partial bottles are not dispensed." Therefore, two bottles must be dispensed to provide the client with a full course of medication. Amount to dispense = 2 bottles × 100 mL/bottle = 200 mL.