Oxcarbazepine has a presumed mechanism of anticonvulsant action the same as that for carbamazepine, namely, binding to the open-channel conformation of the VSSC at a site within the channel itself on the a subunit. However, oxcarbazepine seems to have some important differences from carbamazepine. What are the differences (Select all that applies):

A. Less Sedating: Oxcarbazepine is generally better tolerated than carbamazepine and is associated with less sedation, improving patient alertness and daily functioning. B. Less bone marrow toxicity: Unlike carbamazepine, oxcarbazepine has a lower risk of serious hematologic side effects such as leukopenia, aplastic anemia, or agranulocytosis, making it safer for long-term use. C. Less CYP450 3A4 interactions: Oxcarbazepine is metabolized differently than carbamazepine and exhibits fewer interactions with CYP450 3A4 substrates, reducing the risk of drug-drug interactions. D. Less weight gain: Oxcarbazepine tends to have a more favorable metabolic profile compared to carbamazepine, with lower rates of weight gain reported in clinical studies, enhancing tolerability for long-term therapy.