Paroxetine (Paxil) has been prescribed for a client with a somatic symptom disorder. The nurse instructs the client to watch out for which of the following side effects?

Choice A reason: Nausea is one of the most common side effects of paroxetine, an SSRI. It occurs due to serotonin’s effect on the gastrointestinal tract, where serotonin receptors influence motility and secretion. Clients should be educated to take the medication with food to minimize this effect. Choice B reason: Increased flatulence is not a typical side effect of SSRIs. While gastrointestinal upset can occur, flatulence is not a primary concern with paroxetine. Choice C reason: Increased appetite is more commonly associated with other antidepressants such as mirtazapine. SSRIs like paroxetine may cause weight changes, but nausea and decreased appetite are more frequent. Choice D reason: Constipation is not a primary side effect of paroxetine. SSRIs are more likely to cause diarrhea than constipation due to increased serotonin activity in the gut.