Patient Data For each statement, click to indicate whether the statements by the student nurse indicate understanding or no understanding of naloxone. Each row must have one option selected.

Understanding: "You can give naloxone intravenously, intramuscularly, or subcutaneously." "If the first dose does not work, you can give as many doses as needed to reverse respiratory depression." "Naloxone works best on pure agonist opioids." No Understanding: "Naloxone will not affect the client's level of pain." "When given IV, naloxone starts working immediately and can last several hours." Rationale: "Naloxone will not affect the client's level of pain. This shows no understanding because naloxone blocks all opioid receptors, including those responsible for analgesia. Once naloxone is administered, the client's opioid-induced pain relief is lost, and pain will likely intensify unless managed separately. "You can give naloxone intravenously, intramuscularly, or subcutaneously." This shows understanding because naloxone is approved for IV, IM, and SC administration. IV is preferred for rapid effect in emergencies, while IM or SC may be used when IV access is delayed or unavailable. "When given IV, naloxone starts working immediately and can last several hours." This shows no understanding because naloxone’s onset is rapid when given IV (within 1–2 minutes), but its duration is short, generally lasting 30–90 minutes. It often requires repeated dosing to sustain reversal effects. "If the first dose does not work, you can give as many doses as needed to reverse respiratory depression." This shows understanding because multiple doses of naloxone may be necessary depending on the opioid’s half-life and the severity of respiratory depression. Repeated dosing ensures that ventilation is supported adequately. "Naloxone works best on pure agonist opioids." This shows understanding because naloxone is most effective against pure opioid agonists like morphine, heroin, and fentanyl. It competitively displaces these substances from opioid receptors, reversing their full agonist effects.