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    Pharmacology 6128 midterm Proctored exam

    Patient NJ is a 35-year-old female who comes to your pharmacy complaining of new red, itchy, watery eyes that started as the weather began to change 1 week ago. She has allergy symptoms from time to time and takes a daily antihistamine. She tried Gen Teal Tear Drops 3x a day, but had no success. Rubbing her eyes makes it worse. She states that her symptoms are mild and that this is not a daily occurrence. NJ has no known drug allergies and takes a multivitamin daily and loratadine 10 mg daily. Which of the following OTC options would you recommend to use for her intermittent symptoms?

    Explanation & Rationale

    A. Theratears Gel CMC 1%, sodium bicarbonate: This product is a lubricant eye drop designed to relieve dryness by stabilizing the tear film. It does not address the underlying allergic response, such as histamine release, so it is unlikely to relieve itching, redness, and watering associated with allergic conjunctivitis. B. Opticrom–cromolyn sodium: Cromolyn sodium is a mast cell stabilizer that prevents release of histamine and other mediators. However, it requires consistent, scheduled use over several days to weeks for full effect, making it less suitable for intermittent, mild symptoms needing quick relief. C. Refresh Tears–carboxymethylcellulose 0.5%: This is another artificial tear that helps with lubrication and dryness but does not treat allergic inflammation. Since NJ already tried similar tear drops without success, this would not provide additional benefit for her symptoms. D. Opcon-A–naphazoline 0.02675% and pheniramine 0.315%: This combination provides both an antihistamine effect (pheniramine) to relieve itching and a vasoconstrictor (naphazoline) to reduce redness. It works quickly and is appropriate for short-term, intermittent allergic eye symptoms, aligning well with NJ’s presentation.

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