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    ATI LPN Pharmacology and Dosage Calculation Proctored Exam

    The doctor orders 250 mg of an antibiotic. The stock supply is a vial of 250 mg of the drug. Directions say to reconstitute with 1.7 mL of sterile water to yield 2 mL of the drug. How many milliliters will you give for the correct dose?

    Explanation & Rationale

    Given: Ordered dose of antibiotic: 250 mg Vial contains: 250 mg of antibiotic Reconstitution volume: 1.7 mL of sterile water Final volume after reconstitution: 2 mL Step 1: Determine the concentration of the reconstituted solution: Concentration (mg/mL) = Total amount of drug (mg) / Total volume (mL) Concentration (mg/mL) = 250 mg / 2 mL Concentration (mg/mL) = 125 mg/mL Step 2: Calculate the volume to be administered: Volume (mL) = Ordered dose (mg) / Concentration (mg/mL) Volume (mL) = 250 mg / 125 mg/mL Volume (mL) = 2 mL

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