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    ATI LPN Pharmacology and Dosage Calculation Proctored Exam

    The doctor orders Augmentin 250 mg po q6h. The drug comes in a 2 gram vial. Directions say to reconstitute with 77.2 mL of sterile water to yield a solution of 125 mg/5 mL. How many mL will you administer to the client for the correct dose?

    Explanation & Rationale

    Given: Ordered dose of Augmentin: 250 mg Drug comes in a 2 gram vial Reconstituted volume: 77.2 mL Concentration after reconstitution: 125 mg/5 mL Step 1: Calculate the total volume of the reconstituted solution: Total volume = 77.2 mL Step 2: Calculate the total amount of Augmentin in the solution: Total amount (mg) = Concentration (mg/mL) x Total volume (mL) Total amount (mg) = 125 mg/5 mL x 77.2 mL Total amount (mg) = 1930 mg Step 3: Determine the number of doses in the vial: Number of doses = Total amount (mg) / Ordered dose (mg/dose) Number of doses = 1930 mg / 250 mg/dose Number of doses = 7.72 doses Step 4: Calculate the volume per dose: Volume per dose (mL) = Total volume (mL) / Number of doses Volume per dose (mL) = 77.2 mL / 7.72 doses Volume per dose (mL) = 10 mL

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