Hesi Med-surg proctored exam (MCPHS University)
Calculation
The healthcare provider (HCP) prescribes cefazolin 800 mg IM every six hours. The available vial is labeled, "Cefazolin 1 gram," and the instructions for reconstitution state, for IM use add 2.5 mL sterile water for injection to provide a total volume of 3.0 mL. After reconstitution, the solution contains how many mg/mL? Enter numeric value only. If rounding is required, round to the nearest whole number.)
mg/mL
Explanation & Rationale
Calculation: Total amount of drug and convert to milligrams (mg). Total drug amount = 1 gram = 1000 mg. Total volume of the reconstituted solution = 3.0 mL. Calculate the concentration in milligrams per milliliter (mg/mL). Concentration (mg/mL) = Total drug amount (mg) / Total volume (mL) = 1000 mg / 3.0 mL = 333.333... mg/mL. Round appropriately to the nearest whole number. = 333 mg/mL.
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