The healthcare provider prescribes a continuous IV infusion of nesiritide 0.01 mcg/kg/minute for a client who weighs 155.1 pounds. The pharmacy provides a 250 mL bag of D5W labeled with the additive nesiritide 5 mg. The nurse should program the infusion pump to deliver how many mL/hour? (Enter numeric value only. If rounding is required, round to the nearest whole number.)
Explanation & Rationale
Given: Ordered dose of Nesiritide: 0.01 mcg/kg/minute Patient weight: 155.1 pounds Bag size: 250 mL D5W Concentration of Nesiritide: 1.5 mg Step 1: Convert patient weight from pounds to kilograms: 1 pound (lb) = 0.453592 kilograms (kg) Patient weight in kg = 155.1 lbs x 0.453592 kg/lb = 70.3 kg Step 2: Calculate the total dose of Nesiritide in mcg/minute: Total dose (mcg/minute) = Ordered dose (mcg/kg/minute) x Patient weight (kg) Total dose (mcg/minute) = 0.01 mcg/kg/minute x 70.3 kg Total dose (mcg/minute) = 0.703 mcg/minute Step 3: Convert mcg/minute to mg/hour: Total dose (mg/hour) = Total dose (mcg/minute) x 60 minutes/hour / 1000 mcg/mg Total dose (mg/hour) = 0.703 mcg/minute x 60 minutes/hour / 1000 mcg/mg Total dose (mg/hour) = 0.04218 mg/hour Step 4: Calculate the infusion rate in mL/hour: Infusion rate (mL/hour) = Total dose (mg/hour) / Concentration (mg/mL) Infusion rate (mL/hour) = 0.04218 mg/hour / (1.5 mg/250 mL) Infusion rate (mL/hour) = 0.04218 mg/hour x (250 mL/1.5 mg) Infusion rate (mL/hour) = 7.03 mL/hour Step 5: Round to the nearest whole number: Infusion rate (mL/hour) ≈ 7 mL/hour