The healthcare provider prescribes amoxicillin 500 mg PO every 8 hours for a child who weighs 88 pounds. The recommended maximum safe dose is 50 mg/kg/24 hours. The available suspension is labeled, "Amoxicillin Suspension 250 mg/5 mL. Based on this child's weight, how many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the whole number.)
Explanation & Rationale
First, we need to convert the child’s weight from pounds to kilograms since the dosage is prescribed in mg/kg. We know that 1 kg is approximately 2.20462 pounds. So, Weight in kg= Weight in pounds/2.20462 = 2.2046288 ≈ 39.92kg The prescribed dosage is 500 mg every 8 hours, which means three doses per day (since there are 24 hours in a day). Therefore, the total daily dosage is 500 mg * 3 = 1500 mg. The recommended maximum safe dose is 50 mg/kg/24 hours. Therefore, the maximum safe dosage for this child would be: Maximum safe dosage in mg=Dosage per kg×Weight in kg=50mg/kg×39.92kg=1996mg Since the prescribed daily dosage (1500 mg) is less than the maximum safe dosage (1996 mg), it is safe to administer the prescribed dosage. The medication is available in a concentration of 250 mg/5 mL. Therefore, the volume to be administered per dose in mL would be: Volume in mL= Dosage per dose in mg/ Concentration in mg/mL = 500mg/50mg/mL = 10mL So, the nurse should administer 10 mL of Amoxicillin Suspension per dose.