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    Rn Hesi Dosage Calculations III Proctored Exam
    Calculation

    The healthcare provider prescribes cefazolin 800 mg IM every 6 hours. The available vial is labeled, "Cefazolin 1 gram," and the instructions for reconstitution state, "For IM use, add 2.5 mL sterile water for injection to provide a total volume of 3.0 mL How many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest tenth.)

    mL

    Explanation & Rationale

    Here's how to calculate the volume (mL) the nurse should administer for cefazolin: 1. We know the following: Prescribed dose: 800 mg cefazolin IM every 6 hours (given) Vial content: 1 gram cefazolin (given) However, we need to consider the reconstitution process for accurate dosage calculation. Reconstitution information: For IM use, add 2.5 mL sterile water for injection. This dilution creates a total volume of 3.0 mL. 3. We need to find the concentration of cefazolin in the reconstituted solution (mg/mL). Concentration (mg/mL) = Total drug amount (mg) / Total volume (mL) after reconstitution Concentration (mg/mL) = 1 gram (which is 1000 mg) / 3.0 mL Concentration (mg/mL) = 333.33 mg/mL (round to nearest tenth) 4. Now, we can find the volume to administer for the prescribed dose (800 mg) considering the concentration (333.33 mg/mL) in the reconstituted solution. Volume to administer (mL): Dose (mg) / Concentration (mg/mL) Volume to administer (mL): 800 mg / 333.33 mg/mL Volume to administer (mL): 2.40 mL (round to nearest tenth) Therefore, the nurse should administer approximately 2.4 mL of the reconstituted cefazolin solution intramuscularly.

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