The healthcare provider prescribes filgrastim 5 mcg/kg subqutaneous (SubQ) for a client who weighs 176 pounds. The available vial is labeled, "Filgrastim 300 mcg/mL. Based on the client's weight, how many milliliters should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest tenth.)
Explanation & Rationale
here's how to calculate the volume (mL) of filgrastim the nurse should administer: Client weight conversion: Client weight: 176 pounds Since medication dosage is based on weight per kilogram (kg), we need to convert the weight to kg for accurate calculation. Conversion factor: 1 kg = 2.205 lbs Client weight (kg) = 176 pounds / 2.205 lbs/kg Client weight (kg) = 80 kg (round to nearest whole number) Filgrastim dose per kg: Dose per kg = 5 mcg/kg (given) Filgrastim concentration: The medication vial is labeled 300 mcg/mL. This indicates there are 300 mcg of filgrastim in every 1 mL of solution. We need to find the volume (mL) containing the prescribed dose (based on weight) of filgrastim (5 mcg/kg) considering the concentration (300 mcg/mL) in the vial. Total filgrastim dose (mcg): Dose (mcg/kg) x Client weight (kg) Total filgrastim dose (mcg): 5 mcg/kg * 80 kg Total filgrastim dose (mcg): 400 mcg Volume to administer (mL): Total dose (mcg) / Concentration (mcg/mL) Volume to administer (mL): 400 mcg / 300 mcg/mL Volume to administer (mL) = 1.33 mL (round to nearest tenth) Therefore, the nurse should administer approximately 1.3 mL of filgrastim subcutaneously.