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    Rn Hesi Dosage Calculations III Proctored Exam
    Calculation

    The healthcare provider prescribes filgrastim 5 mcg/kg/day subcutaneously (SubQ) for a client who weighs 132 pounds and has just completed chemotherapy. The medication is available in 480 mcg/0.8 mL. How many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest tenth).

    mL

    Explanation & Rationale

    Here's how to calculate the volume (mL) of filgrastim the nurse should administer: 1. Client weight conversion: Client weight: 132 pounds Medication dosage is based on weight per kilogram (kg). Conversion factor: 1 kg = 2.205 lbs Client weight (kg): 132 pounds / 2.205 lbs/kg = 60 kg (round to nearest whole number) 2. Filgrastim dosage: Prescribed dose: 5 mcg/kg/day (given) 3. Daily filgrastim amount: Daily dose (mcg) = Dose (mcg/kg/day) x Client weight (kg) Daily dose (mcg) = 5 mcg/kg/day * 60 kg Daily dose (mcg) = 300 mcg (round to nearest whole number) 4. Filgrastim vial concentration: The medication is available in 480 mcg/0.8 mL. This indicates the concentration of filgrastim in the vial is 480 mcg per 0.8 mL. 5. We need to find the volume (mL) to administer that provides the daily dose (300 mcg) based on the medication concentration (480 mcg/0.8 mL). Volume to administer (mL) = Daily dose (mcg) / Concentration (mcg/mL) Volume to administer (mL) = 300 mcg / (480 mcg/0.8 mL) To perform the division accurately, we need the concentration in the same units (mcg/mL) for both the numerator and denominator. We can achieve this by multiplying the vial concentration (480 mcg/0.8 mL) by a factor that converts the denominator (0.8 mL) to 1 mL. Factor = 1 mL / 0.8 mL = 1.25 (since 1.25 x 0.8 mL = 1 mL) Apply the factor to adjust the concentration in the denominator: Adjusted concentration = 480 mcg/0.8 mL * 1.25 = 600 mcg/mL Now, calculate the volume to administer: Volume to administer (mL) = 300 mcg / (600 mcg/mL) Volume to administer (mL) = 0.5 mL (round to nearest tenth as requested) Therefore, the nurse should administer approximately 0.5 mL of filgrastim subcutaneously.

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