The healthcare provider prescribes filgrastim 5 mcg/kg/day subcutaneously (SubQ) for a client who weighs 132 pounds and has just completed chemotherapy. The medication is available in 480 mcg/0.8 mL. How many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest tenth).
Explanation & Rationale
Here's how to calculate the volume (mL) of filgrastim the nurse should administer: 1. Convert weight from pounds to kilograms: Weight (kg) = Weight (lb) / 2.2 Weight (kg) = 132 lb / 2.2 Weight (kg) = 60 kg (approximately) 2. Calculate the total filgrastim dose per day: Dose (mcg/kg) x Weight (kg) = Total dose (mcg) 5 mcg/kg x 60 kg = 300 mcg 3. Determine the concentration of filgrastim in the medication (mcg/mL): Concentration (mcg/mL) = Total mcg / Volume (mL) Concentration (mcg/mL) = 480 mcg / 0.8 mL Concentration (mcg/mL) = 600 mcg/mL 4. Calculate the volume (mL) to administer for the prescribed dose (considering the concentration): Volume to administer (mL) = Dose (mcg) / Concentration (mcg/mL) Volume to administer (mL) = 300 mcg / 600 mcg/mL Volume to administer (mL) = 0.5 mL (round to nearest tenth) Therefore, the nurse should administer 0.5 mL of filgrastim subcutaneously.