The healthcare provider prescribes lamivudine oral solution 150 mg twice daily for a client who is HIV positive. The available bottle contains 240 mL of lamivudine labeled, "10 mg/mL." How many mL should the nurse administer in a 24-hour period? (Enter numeric value only.)

- Calculate the dose of lamivudine in mg: 150 mg x 2 = 300 mg - Divide the dose by the concentration to get the volume in mL: 300 mg / 10 mg/mL = 30 mL - Multiply the volume by the number of doses per day to get the total volume in a 24-hour period: 30 mL x 2 = 60 mL - The nurse should administer 60 mL of lamivudine oral solution in a 24-hour period.