The healthcare provider prescribes lamivudine oral solution 150 mg twice daily for a client who is HIV positive. The available bottle contains 240 mL of lamivudine labeled, 10 mg/mL. How many mL should the nurse administer in a 24 hour period? (Enter numeric value only.)

Given: Ordered dose of lamivudine: 150 mg twice daily Concentration of lamivudine solution: 10 mg/mL Step 1: Calculate the total daily dose of lamivudine: Total daily dose (mg) = Dose per administration (mg) x Number of administrations per day Total daily dose (mg) = 150 mg/dose x 2 doses/day Total daily dose (mg) = 300 mg/day Step 2: Calculate the volume to be administered per dose: Volume (mL) = Dose per administration (mg) / Concentration (mg/mL) Volume (mL) = 150 mg / 10 mg/mL Volume (mL) = 15 mL/dose Step 3: Calculate the total volume to be administered in 24 hours: Total volume (mL) = Volume per dose (mL) x Number of doses per day Total volume (mL) = 15 mL/dose x 2 doses/day Total volume (mL) = 30 mL/day