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    Wgu HESI RN Pharmacology 1 Proctored Exam

    The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?

    Explanation & Rationale

    A. Offer both drugs together with a meal: Propylthiouracil (PTU) and Lugol's solution are typically not administered together with a meal. Lugol's solution, a strong iodine solution, is generally taken separately from PTU to avoid potential interactions and ensure optimal absorption of each medication. B. Administer iodine one hour before PTU: Lugol’s solution (iodine) is usually given before PTU because iodine can decrease the vascularity of the thyroid gland and make the thyroid gland less active, which helps PTU work more effectively. This timing helps optimize the therapeutic effects of both medications. C. Schedule both medications at bedtime: The timing of administration for PTU and Lugol’s solution is based on their specific interactions and pharmacokinetics rather than convenience. Scheduling them at bedtime does not align with the recommended practice for their optimal effectiveness. D. Give parental dose once every 24 hours: Both PTU and Lugol’s solution are not administered as a single dose every 24 hours. PTU is typically given multiple times per day to maintain effective blood levels, and Lugol’s solution is usually given as directed by the healthcare provider, often several times a day but not necessarily in a single 24-hour dose.

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