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    Hesi rn d441 pharmacology 0A1 proctored exam

    The healthcare provider prescribes propylthiouracil (PTU) and Lugol's solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?

    Explanation & Rationale

    A) Offer both drugs together with a meal: While some medications can be taken with food to minimize gastrointestinal upset, PTU specifically should be administered on an empty stomach for optimal absorption. Additionally, the timing between these two medications is crucial. B) Schedule both medications at bedtime: This option does not address the necessary timing of iodine administration in relation to PTU. Administering them together at bedtime could lead to ineffective treatment. C) Give parental dose once every 24 hours: This option may be misleading as it does not specify the route or the need for timing between these specific medications. PTU is typically given multiple times a day rather than once every 24 hours. D) Administer iodine one hour before PTU: This is the correct approach. Administering Lugol's solution (iodine) one hour before PTU allows the iodine to suppress thyroid hormone release before PTU takes effect. This staggered administration enhances the therapeutic effects of both medications in managing hyperthyroidism.

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