The nurse administers losartan 50 mg PO to a client. One hour after administration, the client calls the nurse and complains of tingling of the lips. Noting that the client's lips are edematous, the nurse recognizes that the client is experiencing which issue?

A. The client is retaining fluids and will need a fluid restriction: While fluid retention can occur with certain medications, the specific symptoms of tingling lips and edema suggest a different issue, making this option less relevant. B. The client has developed an expected side effect of the medication: Tingling of the lips and lip edema are not typical expected side effects of losartan. This medication can cause side effects like dizziness or hypotension, but angioedema is a serious concern that can occur. C. The client is experiencing angioedema and notifies the healthcare provider: This is the most appropriate interpretation of the symptoms. Angioedema is a potentially serious allergic reaction that can occur with medications such as losartan, which is an angiotensin II receptor blocker. Immediate notification of the healthcare provider is crucial for further evaluation and management. D. The client will need to have the dose of the medication reduced: While reducing the dose might be considered in some cases of side effects, the symptoms described indicate a potentially severe reaction that requires immediate attention rather than simply adjusting the dosage.