The nurse has reviewed the Provider Prescriptions on the day of discharge. Exhibits The nurse has provided information regarding the adolescent's medication for home use to the guardian and the adolescent. Select the 2 statements that demonstrate the guardian's understanding of the adolescent's medication.

A. "This drug won't decrease the effectiveness of their oral contraceptive medication.": Phenytoin induces hepatic enzymes, which increase the metabolism of oral contraceptives and reduce their effectiveness. B. "We will need to periodically have their blood drawn to check phenytoin levels.": Phenytoin has a narrow therapeutic index, and blood levels must be monitored to avoid subtherapeutic dosing or toxic effects such as ataxia, confusion, or nystagmus. C. "This medication may cause their eyes to move quickly back and forth at times.": Nystagmus is a known dose-related adverse effect of phenytoin, especially at higher levels. Recognizing this side effect indicates understanding of possible neurologic manifestations of toxicity. D. "They will need to take 400 international units (IU) of vitamin E while on this medication.": Vitamin E supplementation is not required for adolescents taking phenytoin. Nutritional support may focus more on maintaining adequate folic acid and vitamin D. E. "There is nothing we can do to minimize overgrowth of their gum tissue.": Gingival hyperplasia is a common side effect of phenytoin, but it can be minimized with proper oral hygiene such as regular toothbrushing, flossing, and dental visits.