The nurse initiates an infusion of piperacillin-tazobactam for a client with a urinary tract infection. Five minutes into the infusion, the client reports not feeling well. Which client manifestation should the nurse identify as a reason to stop the infusion?

A. A scratchy throat can be an early sign of an allergic reaction to the antibiotic, which could progress to anaphylaxis if the infusion continues. Immediate cessation of the infusion is essential to prevent serious complications, and the nurse should notify the provider and initiate emergency interventions if needed. B. Pupillary constriction is not a typical sign of an acute allergic reaction to piperacillin-tazobactam and does not warrant stopping the infusion. C. Hypertension is not an expected early manifestation of an allergic reaction to this antibiotic. Blood pressure changes are more likely to occur later if anaphylaxis develops. D. Bradycardia is not commonly associated with an early allergic reaction to antibiotics and does not require immediate cessation of the infusion unless other signs of anaphylaxis are present.