The nurse is administering IV fluconazole to a client who has systemic candidiasis. After reviewing the client's diagnostic studies, the nurse identifies a rising trend in the liver enzyme levels for aspartate aminotransferase (AST). Which action should the nurse implement?
Explanation & Rationale
Choice A reason: Continuing the infusion while monitoring the client's laboratory values is not appropriate when there is a rising trend in liver enzyme levels. This could indicate liver toxicity, and continuing the infusion may worsen the condition.Choice B reason: While notifying the pharmacy to stop dispensing further doses is important, the priority action is to hold the current dose and notify the healthcare provider of the lab changes to get immediate guidance.Choice C reason: Submitting a drug reaction report is part of the process, but the immediate action should be to address the potential liver toxicity by stopping the medication and informing the healthcare provider.Choice D reason: Holding the dose and notifying the healthcare provider of the changes in laboratory studies is the most critical action. Rising AST levels suggest potential hepatotoxicity, and the healthcare provider needs to evaluate the client's condition and make decisions about continuing or discontinuing the medication.