The nurse is admitting a client who has a diagnosis of chronic obstructive pulmonary disease (COPD). The healthcare provider (HCP) prescribes theophylline. Since the therapeutic range for theophylline is narrow, the nurse plans to observe for signs of toxicity. Which symptoms should the nurse identify as related to theophylline toxicity?

Rationale: A. Edema, hypertension, and shortness of breath: These symptoms are more consistent with heart failure or fluid overload rather than theophylline toxicity. Theophylline primarily affects the central nervous and cardiovascular systems when levels become toxic. B. Lethargy, bradycardia, somnolence, and loss of sensorium: These findings suggest severe CNS depression or other metabolic disturbances, not typical of theophylline toxicity. Toxic levels usually cause stimulation rather than suppression of the CNS. C. Vomiting, dizziness, restlessness, and palpitations: Theophylline toxicity presents with gastrointestinal upset (such as nausea and vomiting), central nervous system stimulation (restlessness, insomnia, dizziness), and cardiac manifestations (palpitations, tachycardia, arrhythmias). D. Coughing, wheezing, and gasping for breath: These symptoms are more indicative of worsening COPD or an acute asthma exacerbation. They represent the underlying disease process rather than toxicity from theophylline.